In just a few months, JWST has revolutionized our understanding of the universe. Its unprecedented sensitivity and angular resolution have given us a new view of the cosmos, enabling new discoveries in many areas of astronomy. I will describe first results from my GLASS-JWST Early Release Science Program and a GO program entitled “A Complete Census of Supermassive Black Holes and Host Galaxies at z=6”, aimed at understanding how the first galaxies and black holes form, grow, and cause the last major phase transition of the universe, called “cosmic reionization”. Highlights include: i) the discovery and initial characterization of an hitherto unknown population of luminous galaxies at z>10, indicating that galaxies formed earlier and faster than previously thought; ii) the characterization of the relationship between black holes and their host galaxies at z=6.